Science : Genetics

This beautifully illustrated textbook provides a clear guide to the tools and techniques of genetic engineering, gene cloning and molecular biology. All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Using an example-driven approach, the fundamentals of creating mutations in DNA, cloning in bacteria, yeast, plants and animals are all clearly presented.Strong emphasis is placed on the latest, post genomic technologies including DNA macro and microarrays, genome-wide two hybrid analysis, proteomics and bioinformatics.A modern post-genome era introduction to key techniques used in genetic engineering.An example driven past-to-present approach to allow the experiments of today to be placed in an historical contextThe book is beautifully illustrated in full-colour throughout.Associated website including updates, additional content and illusions  more...

Price: $225.00

The R language is available for a range of computer systems and has been adopted as a computational environment by many authors of statistical software. This book integrates a variety of data analysis methods into the R language. It also gives examples from real biological problems with an emphasis on how things work in an R package. more...

Price: $54.95

An essential resource on movement disorders research that bridges basic and clinical science. more...

Price: $275.00

Oxidation is any reaction in which electrons are removed from a molecule, thus increasing the number of binding sites on the molecule that are able to react with other atoms and molecules. This volume addresses oxidation-reduction (redox) and antioxidant sensitive molecular mechanisms. Recent work in this area has revealed that these mechanisms may be linked with different disease processes, such as immune response, cell proliferation, inflammation, metabolism, aging, and cell death. The chapters provide research findings, as well as summary illustrations and possible strategies to pharmacologically and/or nutritionally manipulate these redox-sensitive molecular responses. more...

Price: $180.00

Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedically-oriented research.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences. more...

Price: $149.95