Medical : Clinical Medicine

A practical "how to" guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods. Edited by the winner of the Oskar-Minkowski Prize of the EASD in 2006. Clinical trials in populations at risk of or with overt diabetes mellitus are being performed all around the world to test novel drugs and approaches to managing these diseases. During the last decade, new methods and techniques have been introduced – and are being developed further – that facilitate monitoring of metabolism and even diagnosis of certain defects in human metabolism. While some of these methods are restricted to research facilities, others are already used in clinical practice. The correct beneficial use of these methods requires knowledge of the nature of the techniques and their clinical relevance. Clinical Diabetes Research: Methods and Techniques provides summaries of established state-of-the art-techniques and introduces the new technologies, evaluating their potential in clinical diabetes research. One section compares the efficacy of all metabolic tests that measure insulin action. Another section describes methods that allow quantification of whole body and intracellular metabolic fluxes relevant to diabetes research. The final section focuses on the planning and pitfalls of clinical studies in the field of metabolism. Each chapter throughout the book combines the theoretical basis of the approach with practical recommendations. There are further chapters on the design of clinical trials and ethical considerations. The publication is timely in view of the impressive development of the methods and techniques with their application to understanding the pathophysiology of diabetes, insulin resistance syndromes, obesity, and the metabolic effects of treatment. Clinical Diabetes Research: Methods and Techniques is of great relevance for researchers (from students and p more...

Price: $165.00

This edition of 'A Clinical Guide to the Treatment of the Human Stress Response' reflects the changes in this field since the beginning of the 1990s. It is designed as a comprehensive and accessible guide to both the clinically relevant physiology and treatment of the human stress response. more...

Price: $69.95

Begins by placing clinical guidelines within the context of the broader movement towards evidence based practice. This book explores the concept of evidence, and defines clinical guidelines and care protocols. It also describes the implementation of guidelines and protocols and the barriers to implementation, and makes suggestions. more...

Price: $45.00

This volume covers diabetes and vascular disease, hypertension and other risk factors, the evidence base for treatment of hypertension in diabetes, and the diagnosis and assessment of hypertension in the diabetic patient. more...

Price: $24.95

What will happen during and after a clinical trial?.; How will a trial affect my quality of life?.; What are the benefits and risks of a trial?.; What does giving consent mean and what will it involve?.; Will I incur costs during and because of the trial?. These are the questions that should be raised every time a health care professional talks through with a patient the pros and cons of entering a clinical trial. Clinical Trials Explained has been designed in consultation with doctors and patients who have taken part in trials, providing an essential and detailed guide to the clinical trials process. It therefore helps both clinicians and patients make well-informed decisions on whether to take part in a clinical trial. more...

Price: $40.00